For US Audiences Only
FOR U.S. HEALTHCARE PROFESSIONALS
FOR U.S. PATIENTS
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IMPORTANT SAFETY INFORMATION

PRESCRIBING INFORMATION | INSTRUCTIONS FOR USE

For US Audiences Only
HOW DOES CYSTADROPS WORK?

CYSTADROPS (sys-tah-drops) is a prescription eye drop that reduces cystine crystals in the cornea with practical, 4 times a day dosing.

  • CYSTADROPS is a viscous solution that coats the entire surface of the cornea.
  • CYSTADROPS penetrates throughout the cornea to reach all layers of the cornea when used as directed.
  • The active ingredient of CYSTADROPS, cysteamine, enters the lysosomes and breaks apart cystine into smaller pieces that can then exit the lysosomes.
Cystadrops coats the cornea and disolves corneal cystine crystals

Watch this video to see why it is important to get treatment for cystine crystals in your cornea.

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HOW EFFECTIVE IS CYSTADROPS?

CYSTADROPS reduced cystine crystals in all layers of the cornea.

CYSTADROPS was approved by the Food and Drug Administration based on studies that demonstrated safety and effectiveness in people with cystinosis.

One study showed a 12% decrease in cystine crystals in the cornea after 30 days of treatment and a 40% decrease in cystine crystals in the cornea after 90 days.

CYSTADROPS penetrated throughout the layers of the cornea and dissolved cystine crystals in every layer.

The cystine crystal reduction was maintained over time when CYSTADROPS was used daily, as directed.

CYSTADROPS reduced cystine crystals in all layers of the cornea the front layer of the eye
WHAT ARE POSSIBLE SIDE EFFECTS OF CYSTADROPS?

The most common side effects are eye pain (stinging), blurred vision, eye irritation (burning), eye redness, discomfort at instillation site (sticky eyes or sticky eyelids), eye itching, watery eyes, medicine deposit on the eye lashes or around the eyes.

Talk to your doctor if you are experiencing any side effects due to treatment.

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Using CYSTADROPS

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Indications and Usage

WHAT is CYSTADROPS?
CYSTADROPS (cysteamine ophthalmic solution) 0.37% is a prescription medicine used to treat corneal cystine crystal deposits in the eye in adults and children with cystinosis.

Important Safety Information

Before starting CYSTADROPS, tell your healthcare provider (HCP) about all your medical conditions, including if you are pregnant or plan to become pregnant, breastfeeding or plan to breastfeed. Tell your HCP about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.

To minimize the risk of contamination, do not touch the dropper tip to the eyelids, surrounding areas, or to any surface. Keep bottle tightly closed when not in use.

What are the possible side effects of CYSTADROPS?
CYSTADROPS may cause side effects including:

The most common side effects of CYSTADROPS are eye pain (stinging), blurred vision, eye irritation (burning), eye redness, discomfort at instillation site (sticky eyes or sticky eyelids), eye itching, watery eyes, medicine deposit on the eye lashes or around the eyes.

These are not all the possible side effects of CYSTADROPS. Call your HCP for medical advice about side effects. You are encouraged to report side effects of prescription drugs to the FDA. Call 1-800-FDA-1088 or visit www.fda.gov/medwatch.

CYSTADROPS® (cysteamine ophthalmic solution), for topical ophthalmic use, is available as 3.8 mg/mL of cysteamine (0.37%) in 5 mL bottles.

INDICATIONS AND IMPORTANT SAFETY INFORMATION

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Important Safety Information

Before starting CYSTADROPS, tell your healthcare provider (HCP) about all your medical conditions, including if you are pregnant or plan to become pregnant, breastfeeding or plan to breastfeed. Tell your HCP about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.